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Showing 1 to 12 of 336 entries
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Erratum to: Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas.

Journal of neuro-oncology

Wu X, Wu F, Xu D, Zhang T.
PMID: 26915103
J Neurooncol. 2016 Apr;127(2):233. doi: 10.1007/s11060-016-2089-x.

No abstract available.

Spontaneous pneumocephalus associated with a melanoma brain metastasis: a Case Report.

Journal of neuro-oncology

Ahn J, Bunevicius A, Sheehan J.
PMID: 33687627
J Neurooncol. 2021 May;152(3):617-619. doi: 10.1007/s11060-021-03728-4. Epub 2021 Mar 09.

No abstract available.

Long-term disease control and treatment outcomes of stereotactic radiosurgery in cavernous sinus meningiomas.

Journal of neuro-oncology

Martinez-Perez R, Florez-Perdomo W, Freeman L, Ung TH, Youssef AS.
PMID: 33772678
J Neurooncol. 2021 May;152(3):439-449. doi: 10.1007/s11060-021-03732-8. Epub 2021 Mar 27.

BACKGROUND: Most of the current knowledge on the clinical effects of stereotactic radiosurgery (SRS) on the treatment of cavernous sinus meningiomas (CSM) is based on series with limited follow-up. However, determining the role of radiation in a tumor with...

The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications.

Journal of neuro-oncology

Robert SM, Vetsa S, Nadar A, Vasandani S, Youngblood MW, Gorelick E, Jin L, Marianayanam N, Erson-Omay EZ, Günel M, Moliterno J.
PMID: 34846640
J Neurooncol. 2021 Nov 30; doi: 10.1007/s11060-021-03874-9. Epub 2021 Nov 30.

INTRODUCTION: Meningiomas are generally considered "benign," however, these tumors can demonstrate variability in behavior and a surprising aggressiveness with elevated rates of recurrence. The advancement of next-generation molecular technologies have led to the understanding of the genomic and epigenomic...

A multi-center prospective study of re-irradiation with bevacizumab and temozolomide in patients with bevacizumab refractory recurrent high-grade gliomas.

Journal of neuro-oncology

Dixit KS, Sachdev S, Amidei C, Kumthekar P, Kruser TJ, Gondi V, Grimm S, Lukas RV, Nicholas MK, Chmura SJ, Fought AJ, Mehta M, Raizer JJ.
PMID: 34689306
J Neurooncol. 2021 Dec;155(3):297-306. doi: 10.1007/s11060-021-03875-8. Epub 2021 Oct 24.

PURPOSE: Survival is dismal for bevacizumab refractory high-grade glioma patients. We prospectively investigated the efficacy of re-irradiation, bevacizumab, and temozolomide in bevacizumab-naïve and bevacizumab-exposed recurrent high-grade glioma, without volume limitations, in a single arm trial.METHODS: Recurrent high-grade glioma patients...

Impact of cerebrospinal fluid flow study in patients undergoing intrathecal chemotherapy via ventricular catheter reservoir.

Journal of neuro-oncology

Eltobgy M, Huntoon K, Musgrave N, Shaikhouni A, Hardesty DA, Giglio P, Elder JB.
PMID: 33860429
J Neurooncol. 2021 May;153(1):161-167. doi: 10.1007/s11060-021-03756-0. Epub 2021 Apr 15.

PURPOSE: Leptomeningeal carcinomatosis (LMC) is a form of CNS cancer metastasis with severe morbidity. Intrathecal chemotherapy (ITC) administration through an implanted ventricular catheter reservoir (IVCR) is often utilized. Additionally, a nuclear imaging flow study can be performed prior to...

Extent, pattern, and prognostic value of MGMT promotor methylation: does it differ between glioblastoma and IDH-wildtype/TERT-mutated astrocytoma?.

Journal of neuro-oncology

Teske N, Karschnia P, Weller J, Siller S, Dorostkar MM, Herms J, von Baumgarten L, Tonn JC, Thon N.
PMID: 34902093
J Neurooncol. 2021 Dec 13; doi: 10.1007/s11060-021-03912-6. Epub 2021 Dec 13.

INTRODUCTION: The cIMPACT-NOW update 6 first introduced glioblastoma diagnosis based on the combination of IDH-wildtype (IDHwt) status and TERT promotor mutation (pTERTmut). In glioblastoma as defined by histopathology according to the WHO 2016 classification, MGMT promotor status is associated...

Effect of antiepileptic drugs in glioma patients on self-reported depression, anxiety, and cognitive complaints.

Journal of neuro-oncology

van der Meer PB, Koekkoek JAF, van den Bent MJ, Dirven L, Taphoorn MJB.
PMID: 33822293
J Neurooncol. 2021 May;153(1):89-98. doi: 10.1007/s11060-021-03747-1. Epub 2021 Apr 06.

INTRODUCTION: AEDs have been associated with depression, anxiety, and cognitive impairment, all frequent complications of glioma and its subsequent treatment, with considerable morbidity and an adverse effect on health-related quality of life. This study aimed to determine the independent...

The SH3PXD2A-HTRA1 fusion transcript is extremely rare in Norwegian sporadic vestibular schwannoma patients.

Journal of neuro-oncology

Taule-Sivertsen P, Bruland O, Håvik AL, Bratland E, Lund-Johansen M, Knappskog PM.
PMID: 34213706
J Neurooncol. 2021 Aug;154(1):35-40. doi: 10.1007/s11060-021-03796-6. Epub 2021 Jul 02.

INTRODUCTION: Vestibular schwannoma (VS) is a benign intracranial tumor in which the underlying genetics is largely uncertain, apart from mutations in the tumor suppressor gene NF2. Alternative tumorigenic mechanisms have been proposed, including a recurrent in-frame fusion transcript of...

Hematological adverse events in the management of glioblastoma.

Journal of neuro-oncology

Garcia CR, Myint ZW, Jayswal R, Wang C, Morgan RM, Butts AR, Weiss HL, Villano JL.
PMID: 34820776
J Neurooncol. 2021 Nov 24; doi: 10.1007/s11060-021-03891-8. Epub 2021 Nov 24.

BACKGROUND: Hematological adverse events (HAEs) are common during treatment for glioblastoma (GBM), usually associated with temozolomide (TMZ). Their clinical value is uncertain, as few investigations have focused on outcomes for HAEs during GBM treatment.METHODS: We combined data from two...

H3K27M-mutant diffuse midline gliomas should be further molecularly stratified: an integrated analysis of 669 patients.

Journal of neuro-oncology

Vuong HG, Le HT, Ngo TNM, Fung KM, Battiste JD, McNall-Knapp R, Dunn IF.
PMID: 34796414
J Neurooncol. 2021 Dec;155(3):225-234. doi: 10.1007/s11060-021-03890-9. Epub 2021 Nov 18.

INTRODUCTION: H3K27M-mutated diffuse midline gliomas (H3-DMGs) are aggressive tumors with a fatal outcome. This study integrating individual patient data (IPD) from published studies aimed to investigate the prognostic impact of different genetic alterations on survival of these patients.METHODS: We...

Selective salvage radiotherapy could provide favorable outcomes in patients with refractory or relapsed primary central nervous system lymphoma.

Journal of neuro-oncology

Kim N, Lim DH, Yoon SE, Kim SJ, Kim WS.
PMID: 34853952
J Neurooncol. 2021 Dec 01; doi: 10.1007/s11060-021-03909-1. Epub 2021 Dec 01.

INTRODUCTION: To date, there is no relevant data supporting the role of salvage radiotherapy (sRT) in patients with refractory or relapsed primary central nervous system lymphoma (PCNSL). Herein, we aimed to investigate the impact of sRT in patients with...

Showing 1 to 12 of 336 entries